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LY2940680

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601067

MBS3601067 is a biochemical targeting LY2940680. LY2940680 (Taladegib) is potent Smoothened (SMO) receptor antagonist. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LY2940680, Biochemical
Full Product Name
LY2940680
Product Synonym Names
LY 2940680; LY-2940680; Taladegib
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
512.502
Suitability
DMSO: >=5.2mg/mL
Target
Smoothened (Smo)
Receptor
Smoothened
Chemical Name
Benzamide, 4-fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)
SMILES
CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F
Molecular Formula
C26H24F4N6O
CAS Number
1258861-20-9

Product Categories/Family for LY2940680 biochemical

Ovarian Cancer; Wnt/Notch/Hedgehog; Cancer

Structure of LY2940680 biochemical

LY2940680 Biochemical – Cat# MBS3601067

Product References and Citations for LY2940680 biochemical

1. Wang C, et al. Nature. 2013 May 16; 497 (7449):338-43.
2. Lauressergues E, et al. Pharmacol Res Perspect. 2016 Mar 4; 4 (2):e00214.
3. Jin G, et al. Arch Pharm Res. 2017 Dec; 40 (12):1390-1393.
4. Lu X, et al. Eur J Med Chem. 2017 Sep 29; 138:384-395.

Other Notes

Small volumes of LY2940680 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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