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LY2886721

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601086

LY2886721 is a highly potent, selective BACE1 aspartyl protease inhibitor with IC50 of 20.3 and 10.2 nM for BACE1 and BACE2. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LY2886721, Biochemical
Full Product Name
LY2886721
Product Synonym Names
LY 2886721; LY-2886721
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
390.407
Suitability
DMSO: >=42mg/mL
Target
BACE
Receptor
BACE
Chemical Name
2-Pyridinecarboxamide, N-[3-[(4aS, 7aS)-2-amino-4a, 5-dihydro-4H-furo[3, 4-d][1, 3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro
SMILES
[H][C@@]12COC[C@@]1(N=C(N)SC2)C1=CC(NC(=O)C2=NC=C(F)C=C2)=CC=C1F|r,c:24,26,28,t:7,13,19,21|
Molecular Formula
C18H16F2N4O2S
CAS Number
1262036-50-9

Product Categories/Family for LY2886721 biochemical

Alzheimer Disease; Metabolic Enzyme/Protease; Neurological Disease

Structure of LY2886721 biochemical

LY2886721 Biochemical – Cat# MBS3601086

Product References and Citations for LY2886721 biochemical

1. Lahiri DK, et al. Alzheimers Dement. 2014 Oct; 10 (5 Suppl):S411-9.
2. May PC, et al. J Neurosci. 2015 Jan 21; 35 (3):1199-210.
3. Kumar D, et al. Eur J Med Chem. 2018 Mar 25; 148:436-452.

Other Notes

Small volumes of LY2886721 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2886721 purchase

MBS3601086 is a biochemical targeting LY2886721.
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