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KN-62

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601138

KN-62 is a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK II) with Ki of 900 nM for rat brain CaMK II. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KN-62, Biochemical
Full Product Name
KN-62
Product Synonym Names
KN 62; KN62
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
721.9
Suitability
10mM in DMSO
Target
CaMK
Receptor
CaMKV; CaMKII
Chemical Name
5-Isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester
SMILES
CN(C(CC1=CC=C(C=C1)OS(=O)(=O)C2=CC=CC3=C2C=CN=C3)C(=O)N4CCN(CC4)C5=CC=CC=C5)S(=O)(=O)C6=CC=CC7=C6C=CN=C7
Molecular Formula
C38H35N5O6S2
CAS Number
127191-97-3

Structure of KN-62 biochemical

Kn-62 Biochemical – Cat# MBS3601138

Product References and Citations for KN-62 biochemical

1. Tokumitsu H, et al. J Biol Chem. 1990 Mar 15; 265 (8):4315-20.
2. Ishikawa N, et al. J Pharmacol Exp Ther. 1990 Aug; 254 (2):598-602.
3. Ito I, et al. Neurosci Lett. 1991 Jan 2; 121 (1-2):119-21.
4. Gargett CE, et al. Br J Pharmacol. 1997 Apr; 120 (8):1483-90.

Other Notes

Small volumes of KN-62 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KN-62 purchase

MBS3601138 is a biochemical targeting KN-62.
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