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GDC-0326

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601160

A potent, selective, orally available PI3Kalpha inhibitor with Ki of 0.2 nM; displays 133, 20 and 33-fold selectivity over PI3Kbeta, PI3Kdelta and PI3Kgamma, respectively. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDC-0326, Biochemical
Full Product Name
GDC-0326
Product Synonym Names
GDC 0326; GDC0326
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
382.424
Suitability
DMSO: 69mg/mL (180.5mM)
Water: Insoluble (<1mg/mL refers to the product slightly soluble or insoluble)
Target
PI3K
Receptor
PI3Kalpha
Chemical Name
(S)-2-((2-(1-isopropyl-1H-1, 2, 4-triazol-5-yl)-5, 6-dihydrobenzo[f]imidazo[1, 2-d][1, 4]oxazepin-9-yl)oxy)propanamide
SMILES
C[C@H](OC1=CC=C2C3=NC(C4=NC=NN4C(C)C)=CN3CCOC2=C1)C(N)=O
Molecular Formula
C19H22N6O3
CAS Number
1282514-88-8

Product Categories/Family for GDC-0326 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of GDC-0326 biochemical

GDC-0326 Biochemical – Cat# MBS3601160

Product References and Citations for GDC-0326 biochemical

1. Heffron TP, et al. J Med Chem. 2016 Feb 11; 59 (3):985-1002.
2. Soler A, et al. Clin Cancer Res. 2016 Dec 1; 22 (23):5805-5817.

Other Notes

Small volumes of GDC-0326 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0326 purchase

MBS3601160 is a biochemical targeting GDC-0326.
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