SAR-405838 (MI-77301)

Name: SAR-405838 (MI-77301); MyBioSource
Brand: MyBioSource
SKU: MBS3601218
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601218

SAR-405838(MI-77301, MI-773) is a potent and highly selective small-molecule inhibitor of MDM2-p53 interaction with Ki of 0.88 nM. More details

$260 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SAR-405838, Biochemical

Full Product Name

SAR-405838

Product Synonym Names

MI-77301; MI-773

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

562.503

Suitability

10mM in DMSO

Target

MDM2-p53

Receptor

Mdm2

Chemical Name

Spiro[3H-indole-3, 3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2, 2-dimethylpropyl)-1, 2-dihydro-N-(trans-4-hydroxycyclohexyl)-2-oxo-, (2'S, 3R, 4'S, 5'R)

SMILES

ClC1=CC=C2C(NC(C23[C@@H](C4=C(F)C(Cl)=CC=C4)[C@H](C(NC5CC[C@@H](O)CC5)=O)N[C@H]3CC(C)(C)C)=O)=C1

Molecular Formula

C29H34Cl2FN3O3

CAS Number

1303607-60-4

Product Categories/Family for SAR-405838 biochemical

Blood cancer; Apoptosis; Cancer

Product References and Citations for SAR-405838 biochemical

1. Wang S, et al. Cancer Res. 2014 Oct 15; 74 (20):5855-65.
2. Bill KL, et al. Clin Cancer Res. 2016 Mar 1; 22 (5):1150-60.
3. Lu J, et al. Oncotarget. 2016 Dec 13; 7 (50):82757-82769.

Other Notes

Small volumes of SAR-405838 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAR-405838 purchase

MBS3601218 is a biochemical targeting SAR-405838.