• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RO-8994

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601239

A highly potent and selective, small-molecule p53-MDM2 inhibitor with HRFT IC50 of 5 nM. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RO-8994, Biochemical
Full Product Name
RO-8994
Product Synonym Names
RO8994
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
613.5067
Suitability
DMSO: >=45mg/mL
Target
MDM2-p53
Receptor
Mdm2; P53
Chemical Name
Spiro[3H-indole-3, 3'-pyrrolidine]-5'-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2, 2-dimethylpropyl)-1, 2-dihydro-2-oxo-, (2'S, 3R, 4'S, 5'R)
SMILES
CC(C)(C)CC1C2(C(C(N1)C(=O)NC3=C(C=C(C=C3)C(=O)N)OC)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O
Molecular Formula
C31H31Cl2FN4O4
CAS Number
1309684-94-3

Product Categories/Family for RO-8994 biochemical

Apoptosis; Cancer

Structure of RO-8994 biochemical

Ro-8994 Biochemical – Cat# MBS3601239

Product References and Citations for RO-8994 biochemical

1. Zhang Z, et al. Bioorg Med Chem. 2014 Aug 1; 22 (15):4001-9.
2. Yu B, et al. Anticancer Agents Med Chem. 2016; 16 (10):1315-24.

Other Notes

Small volumes of RO-8994 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RO-8994 purchase

MBS3601239 is a biochemical targeting RO-8994.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000