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RO-5508887

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601242

A potent, selective BACE inhibitor with IC50 of 30 nM for BACE1, equally potent against BACE2 (IC50=40 nM) . More details

$470 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RO-5508887, Biochemical
Full Product Name
RO-5508887
Product Synonym Names
RO 5508887; RO5508887; RG-7129; RG7129
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
389.338
Target
BACE
Receptor
BACE
Chemical Name
5-Cyano-pyridine-2-carboxylic acid[3-((R)-2-amino-5, 5-difluoro-4-methyl-5, 6-dihydro-4H-[1, 3]oxazin-4-yl)-4-fluorophenyl]amide
SMILES
CC1(C(COC(=N1)N)(F)F)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)C#N)F
Molecular Formula
C18H14F3N5O2
CAS Number
1310347-50-2

Product Categories/Family for RO-5508887 biochemical

Alzheimer Disease; Metabolic Enzyme/Protease; Neurological Disease

Structure of RO-5508887 biochemical

Ro-5508887 Biochemical – Cat# MBS3601242

Product References and Citations for RO-5508887 biochemical

1. Jacobsen H, et al. J Neurosci. 2014 Aug 27; 34 (35):11621-30.

Other Notes

Small volumes of RO-5508887 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RO-5508887 purchase

MBS3601242 is a biochemical targeting RO-5508887.
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