Upadacitinib (ABT-494)

Name: Upadacitinib (ABT-494); MyBioSource
Brand: MyBioSource
SKU: MBS3601246
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601246

Upadacitinib (ABT-494) is a potent and selective JAK1 inhibitor with celluar IC50 of 8 nM, biochemical IC50 of 40 nM. More details

$220 / 1mL*10mM (in DMSO) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Upadacitinib, Biochemical

Full Product Name

Upadacitinib

Product Synonym Names

ABT-494; ABT494; ABT 494

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

380.3676

Suitability

DMSO: >=22mg/mL

Target

JAK

Receptor

JAK1; JAK2

Chemical Name

1-Pyrrolidinecarboxamide, 3-ethyl-4-(3H-imidazo[1, 2-a]pyrrolo[2, 3-e]pyrazin-8-yl)-N-(2, 2, 2-trifluoroethyl)-, (3S, 4R)

SMILES

CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F

Molecular Formula

C17H19F3N6O

CAS Number

1310726-60-3

Product Categories/Family for Upadacitinib biochemical

Rheumatoid Arthritis; Angiogenesis; Inflammation/Immunology

Product References and Citations for Upadacitinib biochemical

1. Genovese MC, et al. Arthritis Rheumatol. 2016 Dec; 68 (12):2857-2866.
2. Kremer JM, et al. Arthritis Rheumatol. 2016 Dec; 68 (12):2867-2877.
3. Mohamed MF, et al. Clin Pharmacokinet. 2016 Dec; 55 (12):1547-1558.

Other Notes

Small volumes of Upadacitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Upadacitinib purchase

MBS3601246 is a biochemical targeting Upadacitinib.