TAK-931 (Simurosertib)

Name: TAK-931 (Simurosertib); MyBioSource
Brand: MyBioSource
SKU: MBS3601316
Price: 310 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601316

TAK-931 (Simurosertib) is a potent, selective, ATP competitive and orally bioavailable inhibitor of Cdc7 with IC50 of More details

$310 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAK-931, Biochemical

Full Product Name

TAK-931

Product Synonym Names

Simurosertib; TAK931

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

341.433

Suitability

DMSO: 75mg/mL (219.66mM)

Target

CDK

Receptor

CDK

Chemical Name

Thieno[3, 2-d]pyrimidin-4(3H)-one, 2-(2S)-1-azabicyclo[2.2.2]oct-2-yl-6-(3-methyl-1H-pyrazol-4-yl)

SMILES

O=C1C2=C(C=C(C3=CNN=C3C)S2)N=C([C@H]4N(CC5)CCC5C4)N1

Molecular Formula

C17H19N5OS

CAS Number

1330782-76-7

Product Categories/Family for TAK-931 biochemical

Colon Cancer; Angiogenesis; Cancer

Product References and Citations for TAK-931 biochemical

1. Charles Locuson, et al. Abstract 5041: Translational pharmacokinetic-pharmacodynamic xenograft model for TAK-931, a small molecule cell division cycle 7 (CDC7) kinase inhibitor. AACR.
2. Kenichi Iwai, et al. Abstract 3073: Potential predictive biomarkers of clinical responses for a novel CDC7-selective inhibitor TAK-931. AACR.

Other Notes

Small volumes of TAK-931 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAK-931 purchase

MBS3601316 is a biochemical targeting TAK-931.