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GSK-2485852

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601322

GSK-2485852 (GSK2485852, GSK5852) is a highly potent, selective HCV NS5B polymerase inhibitor with IC50 of 3.0 and 1.6 nM for HCV genotypes 1a and 1b in replicon assay, respectively. More details

$1100 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK-2485852, Biochemical
Full Product Name
GSK-2485852
Product Synonym Names
GSK2485852; GSK 2485852; GSK-5852
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
554.3718
Target
HCV
Receptor
HCV
Chemical Name
B-[4-[[[5-Cyclopropyl-2-(4-fluorophenyl)-3-[(methylamino)carbonyl]-6-benzofuranyl](methylsulfonyl)amino]methyl]-2-fluorophenyl]boronic acid
SMILES
OB(C1=CC=C(CN(C2=C(C3CC3)C=C4C(C(NC)=O)=C(C5=CC=C(F)C=C5)OC4=C2)S(=O)(C)=O)C=C1F)O
Molecular Formula
C27H25BF2N2O6S
CAS Number
1331942-30-3

Product Categories/Family for GSK-2485852 biochemical

HCV Infection; Microbiology/Virology; Infection

Structure of GSK-2485852 biochemical

GSK-2485852 Biochemical – Cat# MBS3601322

Product References and Citations for GSK-2485852 biochemical

1. Voitenleitner C, et al. Antimicrob Agents Chemother. 2013 Nov; 57 (11):5216-24.
2. Wilfret DA, et al. Clin Pharmacol Drug Dev. 2014 Nov; 3 (6):439-48.
3, Chong PY, et al. J Med Chem. 2019 Feb 14. doi: 10.1021/acs.jmedchem.8b01719.

Other Notes

Small volumes of GSK-2485852 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-2485852 purchase

MBS3601322 is a biochemical targeting GSK-2485852.
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