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Itacitinib (INCB-039110)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601330

MBS3601330 is a biochemical targeting Itacitinib. A potent and selective JAK1 inhibitor. More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Itacitinib, Biochemical
Full Product Name
Itacitinib
Product Synonym Names
INCB-039110
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
553.5142
Suitability
DMSO: >=30mg/mL
Target
JAK
Receptor
JAK1
Chemical Name
3-Azetidineacetonitrile, 1-[1-[[3-fluoro-2-(trifluoromethyl)-4-pyridinyl]carbonyl]-4-piperidinyl]-3-[4-(7H-pyrrolo[2, 3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]
SMILES
N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1
Molecular Formula
C26H23F4N9O
CAS Number
1334298-90-6

Product Categories/Family for Itacitinib biochemical

Blood cancer; Angiogenesis; Cancer

Structure of Itacitinib biochemical

Itacitinib INCB-039110 Biochemical – Cat# MBS3601330

Product References and Citations for Itacitinib biochemical

1. Zhang Y, et al. Drug Metab Dispos. 2015 Apr; 43 (4):485-9.
2. Kim MK, et al. J Med Chem. 2015 Sep 24; 58 (18):7596-602.
3. Norman P. Expert Opin Investig Drugs. 2014 Aug; 23 (8):1067-77.

Other Notes

Small volumes of Itacitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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