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Pagoclone ((+)-RP-59037)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601348

A potent, orally active GABAA receptor agonist with high affinity (0.7-9.1nM) to the benzodiazepine binding site of GABAA receptors containing either an alpha1, alpha2, alpha3 or alpha5 subunit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Pagoclone, Biochemical
Full Product Name
Pagoclone
Product Synonym Names
(+)-RP-59037; IP-456; RP-62955; CI-1043
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
407.89268
Suitability
10mM in DMSO
Target
GAT
Receptor
GAT
Chemical Name
1H-Isoindol-1-one, 2-(7-chloro-1, 8-naphthyridin-2-yl)-2, 3-dihydro-3-(5-methyl-2-oxohexyl)-, (+)
SMILES
O=C1N(C2=NC3=NC(Cl)=CC=C3C=C2)C(CC(CCC(C)C)=O)C4=C1C=CC=C4
Molecular Formula
C23H22ClN3O2
CAS Number
133737-32-3

Product References and Citations for Pagoclone biochemical

1. Atack JR. Expert Opin Investig Drugs. 2005 May; 14 (5):601-18.
2. Atack JR, et al. Neuropharmacology. 2006 May; 50 (6):677-89.
3. Caveney AF, et al. Neuropsychiatr Dis Treat. 2008 Feb; 4 (1):277-82.

Other Notes

Small volumes of Pagoclone biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pagoclone purchase

MBS3601348 is a biochemical targeting Pagoclone.
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