Doravirine (MK-1439)

Name: Doravirine (MK-1439); MyBioSource
Brand: MyBioSource
SKU: MBS3601354
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601354

Doravirine (MK-1439, MK1439) is a novel, highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 12, 9.7, and 9.7 nM against WT, K103N, and Y181C reverse transcriptase (RT) mutants, respectively. More details

$245 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Doravirine, Biochemical

Full Product Name

Doravirine

Product Synonym Names

MK-1439; MK1439

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

425.7491

Suitability

DMSO: >=30mg/mL

Target

HIV

Receptor

HIV-1

Chemical Name

Benzonitrile, 3-chloro-5-[[1-[(4, 5-dihydro-4-methyl-5-oxo-1H-1, 2, 4-triazol-3-yl)methyl]-1, 2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]

SMILES

N#CC1=CC(OC2=C(C(F)(F)F)C=CN(CC(N3C)=NNC3=O)C2=O)=CC(Cl)=C1

Molecular Formula

C17H11ClF3N5O3

CAS Number

1338225-97-0

Product Categories/Family for Doravirine biochemical

HIV Infection; Microbiology/Virology; Infection

Product References and Citations for Doravirine biochemical

1. Lai MT, et al. Antimicrob Agents Chemother. 2014; 58 (3):1652-63.
2. Ctie B, et al. Bioorg Med Chem Lett. 2014 Feb 1; 24 (3):917-22.
3. Feng M, et al. Antimicrob Agents Chemother. 2015 Jan; 59 (1):590-8.

Other Notes

Small volumes of Doravirine biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Doravirine purchase

MBS3601354 is a biochemical targeting Doravirine.