Linerixibat (GSK-2330672)

Name: Linerixibat (GSK-2330672); MyBioSource
Brand: MyBioSource
SKU: MBS3601389
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601389

A highly potent, selective, ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor with IC50 of 2.1/1.9 nM for mouse/rat ASBT, respectively. More details

$285 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Linerixibat, Biochemical

Full Product Name

Linerixibat

Product Synonym Names

GSK-2330672; GSK2330672

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

546.679

Suitability

DMSO: 21.5mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)

Target

ASBT Transporter

Receptor

hASBT

Chemical Name

3-[[[(3R, 5R)-3-Butyl-3-ethyl-2, 3, 4, 5-tetrahydro-7-methoxy-1, 1-dioxido-5-phenyl-1, 4-benzothiazepin-8-yl]methyl]amino]pentanedioic acid

SMILES

O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2(=O)=O)CC(O)=O

Molecular Formula

C28H38N2O7S

CAS Number

1345982-69-5

Product Categories/Family for Linerixibat biochemical

Diabetes; Membrane Transporter/Ion Channel; Metabolic Disease

Product References and Citations for Linerixibat biochemical

1. Wu Y, et al. J Med Chem. 2013 Jun 27; 56 (12):5094-114.
2. Nunez DJ, et al. Diabetes Obes Metab. 2016 Jul; 18 (7):654-62.
3. Hegade VS, et al. Lancet. 2017 Mar 18; 389 (10074):1114-1123.

Other Notes

Small volumes of Linerixibat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Linerixibat purchase

MBS3601389 is a biochemical targeting Linerixibat.