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Tirabrutinib (ONO4059)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601422

MBS3601422 is a biochemical targeting Tirabrutinib. A potent, selective, third-generation irreversible inhibitor of mutant EGFR. More details

$215 / 1mL*10mM (in DMSO) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tirabrutinib, Biochemical
Full Product Name
Tirabrutinib
Product Synonym Names
ONO4059; ONO-4059; GS4059; GS 4059; GS-4059
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
454.4806
Suitability
10mM in DMSO
Target
BTK
Receptor
BTK
Chemical Name
8H-Purin-8-one, 6-amino-7, 9-dihydro-9-[(3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)
SMILES
CC#CC(=O)N1CCC(C1)N2C3=NC=NC(=C3N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Molecular Formula
C25H22N6O3
CAS Number
1351636-18-4

Product Categories/Family for Tirabrutinib biochemical

Blood cancer; Tyrosine Kinase; Cancer

Structure of Tirabrutinib biochemical

Tirabrutinib ONO4059 Biochemical – Cat# MBS3601422

Product References and Citations for Tirabrutinib biochemical

1. Walter HS, et al. Blood. 2016 Jan 28; 127 (4):411-9.
2. Yahiaoui A, et al. PLoS One. 2017 Feb 8; 12 (2):e0171221.
3. Yasuhiro T, et al. Leuk Lymphoma. 2017 Mar; 58 (3):699-707.

Other Notes

Small volumes of Tirabrutinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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