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GNE-7915

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601423

A highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 1.9 nM. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNE-7915, Biochemical
Full Product Name
GNE-7915
Product Synonym Names
GNE7915; GNE 7915
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
443.3954
Suitability
DMSO: 14.33mg/mL
Target
LRRK2
Receptor
LRRK2
Chemical Name
Methanone, [4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl
SMILES
O=C(C1=CC(OC)=C(NC2=NC=C(C(F)(F)F)C(NCC)=N2)C=C1F)N3CCOCC3
Molecular Formula
C19H21F4N5O3
CAS Number
1351761-44-8

Product Categories/Family for GNE-7915 biochemical

Parkinson Disease; Autophagy; Neurological Disease

Structure of GNE-7915 biochemical

GNE-7915 Biochemical – Cat# MBS3601423

Product References and Citations for GNE-7915 biochemical

1. Estrada AA, et al. J Med Chem. 2012 Nov 26; 55 (22):9416-33.
2. Fuji RN, et al. Sci Transl Med. 2015 Feb 4; 7 (273):273ra15.
3. Kavanagh ME, et al. Bioorg Med Chem Lett. 2013 Jul 1; 23 (13):3690-6.

Other Notes

Small volumes of GNE-7915 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNE-7915 purchase

MBS3601423 is a biochemical targeting GNE-7915.
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