Ew-7197 (Vactosertib)

Name: Ew-7197 (Vactosertib); MyBioSource
Brand: MyBioSource
SKU: MBS3601430
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601430

EW-7197 (Vactosertib, TEW-7197) is a highly potent, selective inhibitor of TGF-beta type I receptor kinase (ALK5) with IC50 of 11 nM. More details

$250 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EW-7197, Biochemical

Full Product Name

EW-7197

Product Synonym Names

Vactosertib; EW7197; TEW-7197

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

399.4236

Suitability

10mM in DMSO

Target

TGFBR

Receptor

ALK1; ALK2; ALK3; ALK4; ALK5

Chemical Name

1H-Imidazole-2-methanamine, N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1, 2, 4]triazolo[1, 5-a]pyridin-6-yl

SMILES

FC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2

Molecular Formula

C22H18FN7

CAS Number

1352608-82-2

Product Categories/Family for EW-7197 biochemical

Blood cancer; TGF-beta/Smad; Cancer

Product References and Citations for EW-7197 biochemical

1. Jin CH, et al. J Med Chem. 2014 May 22; 57 (10):4213-38.
2. Son JY, et al. Mol Cancer Ther. 2014 Jul; 13 (7):1704-16.
3. Yoon JH, et al. EMBO Mol Med. 2013 Nov; 5 (11):1720-39.

Other Notes

Small volumes of EW-7197 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EW-7197 purchase

MBS3601430 is a biochemical targeting EW-7197.