Leniolisib (CDZ-173)

Name: Leniolisib (CDZ-173); MyBioSource
Brand: MyBioSource
SKU: MBS3601446
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601446

A novel potent and selective PI3Kdelta inhibitor with biochemical IC50 of 11 nM; displays >20-fold, 40-fold, and 200-fold selectivity over PI3Kalpha, PI3Kbeta, and PI3Kgamma, respectively. More details

$305 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Leniolisib, Biochemical

Full Product Name

Leniolisib

Product Synonym Names

CDZ-173; CDZ173

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

450.4574

Suitability

DMSO: >=150mg/mL

Target

PI3K

Receptor

PI3Kdelta; PI3Kalpha; PI3Kbeta; DNA-PK

Chemical Name

1-Propanone, 1-[(3S)-3-[[5, 6, 7, 8-tetrahydro-6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]pyrido[4, 3-d]pyrimidin-4-yl]amino]-1-pyrrolidinyl]

SMILES

CCC(=O)N1CCC(C1)NC2=NC=NC3=C2CN(CC3)C4=CC(=C(N=C4)OC)C(F)(F)F

Molecular Formula

C21H25F3N6O2

CAS Number

1354690-24-6

Product Categories/Family for Leniolisib biochemical

Other Disease; PI3K/Akt/mTOR signaling; Other Indications

Product References and Citations for Leniolisib biochemical

1. Klemens Hoegenauer, et al. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00293
2.Rao VK, et al. Blood. 2017 Nov 23; 130 (21):2307-2316.

Other Notes

Small volumes of Leniolisib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Leniolisib purchase

MBS3601446 is a biochemical targeting Leniolisib.