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SB-218078

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601474

A potent inhibitor of Chk1 that blocks phosphorylation of cdc25 with IC50 of 15 nM. More details

$405 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-218078, Biochemical
Full Product Name
SB-218078
Product Synonym Names
SB 218078; SB218078
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
393.4
Target
Chk
Receptor
Chk
Chemical Name
5, 6, 7, 8-tetrahydro-13H-16-oxa-4b, 8a, 14-triaza-5, 8-methanodibenzo[b, h]cycloocta[jkl]cyclopenta[e]-as-indacene-13, 15(14H)-dione
SMILES
O=C1NC(C(C2=C3N([C@@]4([H])CC[C@]5([H])O4)C6=CC=CC=C62)=C1C7=C3N5C8=CC=CC=C78)=O
Molecular Formula
C24H15N3O3
CAS Number
135897-06-2

Product Categories/Family for SB-218078 biochemical

Angiogenesis

Structure of SB-218078 biochemical

Sb-218078 Biochemical – Cat# MBS3601474

Product References and Citations for SB-218078 biochemical

1. Jackson JR, et al. Cancer Res. 2000 Feb 1; 60 (3):566-72.
2. Fishler T, et al. Oncogene. 2010 Jul 15; 29 (28):4007-17.
3. Akasaka T, et al. Int J Oncol. 2015 Jan; 46 (1):63-70.

Other Notes

Small volumes of SB-218078 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB-218078 purchase

MBS3601474 is a biochemical targeting SB-218078.
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