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AVL-292 besylate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601478

AVL-292 besylate (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of More details

$875 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AVL-292 besylate, Biochemical
Full Product Name
AVL-292 besylate
Product Synonym Names
Spebrutinib besylate; CC-292 besylate
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
581.6152
Suitability
10mM in DMSO
Target
BTK
Receptor
BTK
Chemical Name
2-Propenamide, N-[3-[[5-fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-, benzenesulfonate(1:1)
SMILES
COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O
Molecular Formula
C28H28FN5O6S
CAS Number
1360053-81-1

Product Categories/Family for AVL-292 besylate biochemical

Rheumatoid Arthritis; Tyrosine Kinase; Inflammation/Immunology

Structure of AVL-292 besylate biochemical

AVL-292 besylate Biochemical – Cat# MBS3601478

Product References and Citations for AVL-292 besylate biochemical

1. Evans EK, et al. J Pharmacol Exp Ther. 2013 Aug; 346 (2):219-28.
2. Eda H, et al. Leukemia. 2014 Sep; 28 (9):1892-901.
3. Wang X, et al. Mol Cancer Ther. 2016 Sep; 15 (9):2198-208.

Other Notes

Small volumes of AVL-292 besylate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AVL-292 besylate purchase

MBS3601478 is a biochemical targeting AVL-292 besylate.
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