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VHL-IN-15

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601483

VHL-IN-15 is a potent (IC50=4.1 uM) von Hippel–Lindau protein (VHL) ligand that disrupts the VHL/HIF-1alpha interaction. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VHL-IN-15, Biochemical
Full Product Name
VHL-IN-15
Product Synonym Names
VHL-IN 15; VHL IN-15; VHL-IN-15
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
410.43
Target
E3 Ubiquitin Ligase
Receptor
E3 Ubiquitin Ligase
Chemical Name
(2S, 4R)-4-hydroxy-1-(2-(3-methylisoxazol-5-yl)acetyl)-N-(4-(oxazol-5-yl)benzyl)pyrrolidine-2-carboxamide
SMILES
O=C([C@H]1N(C(CC2=CC(C)=NO2)=O)C[C@H](O)C1)NCC3=CC=C(C4=CN=CO4)C=C3
Molecular Formula
C21H22N4O5
CAS Number
1360616-29-0

Product Categories/Family for VHL-IN-15 biochemical

Proteasome/Ubiquitin

Structure of VHL-IN-15 biochemical

VHL-IN-15 Biochemical – Cat# MBS3601483

Product References and Citations for VHL-IN-15 biochemical

1. Buckley DL, et al. J Am Chem Soc. 2012 Mar 14; 134 (10):4465-8.
2. Van Molle I, et al. Chem Biol. 2012 Oct 26; 19 (10):1300-12.

Other Notes

Small volumes of VHL-IN-15 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VHL-IN-15 purchase

MBS3601483 is a biochemical targeting VHL-IN-15.
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