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RO-5353

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601486

MBS3601486 is a biochemical targeting RO-5353. A potent, selective, and orally active p53-MDM2 antagonist with IC50 of 7 nM. More details

$1250 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RO-5353, Biochemical
Full Product Name
RO-5353
Product Synonym Names
RO5353; RO 5353
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
619.533
Target
MDM2-p53
Receptor
MDM2-p53
Chemical Name
(2S, 3R, 4R, 5R)-N-(4-carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-neopentyl-5'-oxo-4', 5'-dihydrospiro[pyrrolidine-3, 6'-thieno[3, 2-b]pyrrole]-5-carboxamide
SMILES
CC(C)(C)CC1C2(C(C(N1)C(=O)NC3=C(C=C(C=C3)C(=O)N)OC)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(S5)Cl)NC2=O
Molecular Formula
C29H29Cl2FN4O4S
CAS Number
1360821-61-9

Product Categories/Family for RO-5353 biochemical

Apoptosis

Structure of RO-5353 biochemical

Ro-5353 Biochemical – Cat# MBS3601486

Product References and Citations for RO-5353 biochemical

1. Zhang Z, et al. ACS Med Chem Lett. 2013 Dec 29; 5 (2):124-7.

Other Notes

Small volumes of RO-5353 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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