Glecaprevir (ABT 493)

Name: Glecaprevir (ABT 493); MyBioSource
Brand: MyBioSource
SKU: MBS3601511
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601511

Glecaprevir (ABT 493;A 1282576) is a novel HCV NS3/4A protease inhibitor with pan-genotypic activity, inhibits NS3/4A proteases from HCV genotypes 1-6 in vitro with IC50 of 3.5-11.3 nM. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glecaprevir, Biochemical

Full Product Name

Glecaprevir

Product Synonym Names

ABT 493; A 1282576

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

838.87

Suitability

DMSO: 80mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)

Target

HCV

Receptor

HCVNS3/4Aprotease

Chemical Name

(33R, 35S, 91R, 92R, 5S, E)-5-(tert-butyl)-N-((1R, 2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-14, 14-difluoro-4, 7-dioxo-2, 8, 10-trioxa-6-aza-1(2, 3)-quinoxalina-3(3, 1)-pyrrolidina-9(1, 2)-cyclopentanacyclotetradecaphan-12-ene-35

SMILES

CC1(CC1)S(=O)(=O)NC(=O)C2(CC2C(F)F)NC(=O)C3CC4CN3C(=O)C(NC(=O)OC5CCCC5OCC=CC(C6=NC7=CC=CC=C7N=C6O4)(F)F)C(C)(C)C

Molecular Formula

C38H46F4N6O9S

CAS Number

1365970-03-1

Product Categories/Family for Glecaprevir biochemical

HCV Infection; Microbiology/Virology; Infection

Product References and Citations for Glecaprevir biochemical

1. Lawitz EJ, et al. Antimicrob Agents Chemother. 2015 Dec 28; 60 (3):1546-55.
2. Gane E, et al. Gastroenterology. 2016 Oct; 151 (4):651-659.e1.
3. Poordad F, et al. Hepatology. 2017 Aug; 66 (2):389-397.

Other Notes

Small volumes of Glecaprevir biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Glecaprevir purchase

MBS3601511 is a biochemical targeting Glecaprevir.