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GNE-0877

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601549

GNE-7915 is a highly potent, selective, brain-penetrating LRRK2 inhibitor with Ki of 0.6 nM (LRRK2 G2019S), pLRRK2 cell IC50 of 3 nM. More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNE-0877, Biochemical
Full Product Name
GNE-0877
Product Synonym Names
GNE0877
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
339.326
Suitability
DMSO: 62mg/mL (182.7mM)
Ethanol: <1mg/mL
Water: <1mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)
Target
LRRK2
Receptor
LRRK2
Chemical Name
2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile
SMILES
CC(N1N=C(C)C(NC2=NC=C(C(F)(F)F)C(NC)=N2)=C1)(C)C#N
Molecular Formula
C14H16F3N7
CAS Number
1374828-69-9

Product Categories/Family for GNE-0877 biochemical

Autophagy; Neurological Disease

Structure of GNE-0877 biochemical

GNE-0877 Biochemical – Cat# MBS3601549

Product References and Citations for GNE-0877 biochemical

1. Fuji RN, et al. Sci Transl Med. 2015 Feb 4; 7 (273):273ra15.

Other Notes

Small volumes of GNE-0877 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNE-0877 purchase

MBS3601549 is a biochemical targeting GNE-0877.
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