Macozinone (PBTZ169)

Name: Macozinone (PBTZ169); MyBioSource
Brand: MyBioSource
SKU: MBS3601559
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601559

Macozinone (PBTZ-169, PBTZ169) is a potent, second-generation antituberculosis agent that inhibits DprE1 and displays nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Macozinone, Biochemical

Full Product Name

Macozinone

Product Synonym Names

PBTZ169; PBTZ-169

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

456.484

Suitability

DMSO: 6.4mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)

Target

Antibacterial

Receptor

DprE1

Chemical Name

2-[4-(cyclohexylmethyl)piperazin-1-yl]-8-nitro-6-(trifluoromethyl)-4H-1, 3-benzothiazin-4-one

SMILES

O=C1N=C(N2CCN(CC3CCCCC3)CC2)SC4=C([N+]([O-])=O)C=C(C(F)(F)F)C=C14

Molecular Formula

C20H23F3N4O3S

CAS Number

1377239-83-2

Product Categories/Family for Macozinone biochemical

Bacterial Infection; GPCR/G Protein; Infection

Product References and Citations for Macozinone biochemical

1. Makarov V, et al. EMBO Mol Med. 2014 Mar; 6 (3):372-83.
2. Makarov V, et al. Antimicrob Agents Chemother. 2015 Aug; 59 (8):4446-52.
3. Gonzalez-Martinez NA, et al. PLoS Negl Trop Dis. 2015 Oct 16; 9 (10):e0004022.
4. Lechartier B, et al. Antimicrob Agents Chemother. 2015 Aug; 59 (8):4457-63.

Other Notes

Small volumes of Macozinone biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Macozinone purchase

MBS3601559 is a biochemical targeting Macozinone.