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Mertansine (DM1)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601649

Mertansine (DM1) is a tubulin inhibitor; thiol-containing maytansinoid that create an antibody-drug conjugate (ADC); an ADC payload. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mertansine, Biochemical
Full Product Name
Mertansine
Product Synonym Names
DM1; Maytansinoid DM1; DM-1; Maytansinoid DM-1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
738.2877
Suitability
DMSO: >=83.33mg/mL
Target
ADC Cytotoxin
Receptor
Others
Chemical Name
Maytansine, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)
SMILES
C[C@@H]1[C@@H]2C[C@]([C@@H](/C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@H]([C@]4(C1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCS)C)/C)OC)(NC(=O)O2)O
Molecular Formula
C35H48ClN3O10S
CAS Number
139504-50-0

Product References and Citations for Mertansine biochemical

1. Niculescu-Duvaz I. Curr Opin Mol Ther. 2010 Jun; 12 (3):350-60.
2. Lambert JM. Br J Clin Pharmacol. 2013 Aug; 76 (2):248-62.
3. Helft PR, et al. Clin Cancer Res. 2004 Jul 1; 10 (13):4363-8.

Other Notes

Small volumes of Mertansine biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mertansine purchase

MBS3601649 is a biochemical targeting Mertansine.
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