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Pyrotinib maleate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601662

Pyrotinib maleate (SHR-1258 maleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50 of 13/38 nM, respectively. More details

$540 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pyrotinib maleate, Biochemical
Full Product Name
Pyrotinib maleate
Product Synonym Names
SHR-1258 maleate; SHR1258 maleate
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
699.161
Suitability
H2O: >=106mg/mL (130.03mM)
Target
EGFR
Receptor
EGFR
Chemical Name
(R, E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-3-(1-methylpyrrolidin-2-yl)acrylamide dimaleate
SMILES
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CC5CCCN5C.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Molecular Formula
C36H35ClN6O7
CAS Number
1397922-61-0

Product Categories/Family for Pyrotinib maleate biochemical

Breast Cancer; Angiogenesis; Cancer

Structure of Pyrotinib maleate biochemical

Pyrotinib Maleate Biochemical – Cat# MBS3601662

Product References and Citations for Pyrotinib maleate biochemical

1. Li X, et al. Eur J Pharm Sci. 2017 Jan 21. pii: S0928-0987 (17)30043-X.

Other Notes

Small volumes of Pyrotinib maleate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pyrotinib maleate purchase

MBS3601662 is a biochemical targeting Pyrotinib maleate.
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