CKD-519 (Rocacetrapib)

Name: CKD-519 (Rocacetrapib); MyBioSource
Brand: MyBioSource
SKU: MBS3601682
Price: 440 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601682

CKD-519 (Rocacetrapib, CKD519) is a potent, selective cholesteryl ester transfer protein (CETP) inhibitor, inhibits the CETP-mediated transfer of cholesteryl ester in human serum with IC50 of 2.3 nM. More details

$440 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CKD-519, Biochemical

Full Product Name

CKD-519

Product Synonym Names

Rocacetrapib; CKD519

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

601.606

Target

CETP

Receptor

CETP

Chemical Name

(4S, 5R)-5-[3, 5-bis(trifluoromethyl)phenyl]-3-({2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5, 5-dimethylcyclohex-1-en-1-yl}methyl)-4-methyl-1, 3-oxazolidin-2-one

SMILES

C[C@H]1[C@@H](C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)OC(N1CC3=C(CCC(C)(C)C3)C4=C(OC)C=C(F)C(C(C)C)=C4)=O

Molecular Formula

C31H34F7NO3

CAS Number

1402796-27-3

Product Categories/Family for CKD-519 biochemical

Dyslipidemia; Metabolic Enzyme/Protease; Cardiovascular Disease

Product References and Citations for CKD-519 biochemical

1. Kim CO, et al. Drug Des Devel Ther. 2016 Nov 15; 10:3763-3770. eCollection 2016.
2. Lee S. Abstract 11228: a novel and potent CETP inhibitor, CKD-519 exerts strong HDL increment and anti-atherosclerotic effects. Circulation. 2013; 128 (Suppl 22):A11228.

Other Notes

Small volumes of CKD-519 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CKD-519 purchase

MBS3601682 is a biochemical targeting CKD-519.