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RO 2443

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601736

RO 2443 is a potent, dual MDM2/MDMX antagonist that inhibits both MDM2 (IC50=33 nM) and MDMX (IC50=41 nM) binding to p53. More details

$875 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RO 2443, Biochemical
Full Product Name
RO 2443
Product Synonym Names
RO2443
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
401.798
Target
MDM2-p53
Receptor
MDM2-p53
Chemical Name
2, 4-Imidazolidinedione, 5-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-3-[(3, 4-difluorophenyl)methyl]
Molecular Formula
C20H14ClF2N3O2
CAS Number
1416663-79-0

Product Categories/Family for RO 2443 biochemical

Apoptosis

Structure of RO 2443 biochemical

Ro 2443 Biochemical – Cat# MBS3601736

Product References and Citations for RO 2443 biochemical

1. Graves B, et al. Proc Natl Acad Sci U S A. 2012 Jul 17; 109 (29):11788-93.

Other Notes

Small volumes of RO 2443 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RO 2443 purchase

MBS3601736 is a biochemical targeting RO 2443.
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