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Pr-924 (IPSI)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601737

MBS3601737 is a biochemical targeting PR-924. A potent, specific immunoproteasome LMP7 subunit inhibitor with IC50 of 25 nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PR-924, Biochemical
Full Product Name
PR-924
Product Synonym Names
IPSI; PR 924; PR924
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
618.734
Target
Proteasome
Receptor
Proteasome
Chemical Name
N-((R)-1-(((S)-3-(1H-indol-3-yl)-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-3-methyl-1H-indene-2-carboxamide
SMILES
C[C@H](C(N[C@H](C(N[C@H](C([C@]1(CO1)C)=O)Cc2ccccc2)=O)Cc(c[nH]3)c4c3cccc4)=O)NC(C5=C(c6c(C5)cccc6)C)=O
Molecular Formula
C37H38N4O5
CAS Number
1416709-79-9

Product Categories/Family for PR-924 biochemical

Proteasome/Ubiquitin

Structure of PR-924 biochemical

Pr-924 IPSI Biochemical – Cat# MBS3601737

Product References and Citations for PR-924 biochemical

1. Parlati F, et al. Blood. 2009 Oct 15; 114 (16):3439-47.
2. de Bruin G, et al. J Med Chem. 2014 Jul 24; 57 (14):6197-209.

Other Notes

Small volumes of PR-924 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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