Acalabrutinib (ACP-196)

Name: Acalabrutinib (ACP-196); MyBioSource
Brand: MyBioSource
SKU: MBS3601758
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601758

A novel, irreversible, covalent second-generation BTK inhibitor with IC50 of 3 nM. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Acalabrutinib, Biochemical

Full Product Name

Acalabrutinib

Product Synonym Names

ACP-196; APC196

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

465.5065

Suitability

DMSO: >=31mg/mL

Target

BTK

Receptor

BTK

Chemical Name

Benzamide, 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1, 5-a]pyrazin-1-yl]-N-2-pyridinyl

SMILES

O=C(NC1=NC=CC=C1)C2=CC=C(C3=C4C(N)=NC=CN4C([C@H]5N(C(C#CC)=O)CCC5)=N3)C=C2

Molecular Formula

C26H23N7O2

CAS Number

1420477-60-6

Product Categories/Family for Acalabrutinib biochemical

Blood cancer; Tyrosine Kinase; Cancer

Product References and Citations for Acalabrutinib biochemical

1. Byrd JC, et al. N Engl J Med. 2016 Jan 28; 374 (4):323-32.
2. Herman SEM, et al. Clin Cancer Res. 2017 Jul 15; 23 (14):3734-3743.
3. Niemann CU, et al. Clin Cancer Res. 2017 Jun 23. pii: clincanres.0650.2017.

Other Notes

Small volumes of Acalabrutinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Acalabrutinib purchase

MBS3601758 is a biochemical targeting Acalabrutinib.