AZD-9291 (Osimertinib)

Name: AZD-9291 (Osimertinib); MyBioSource
Brand: MyBioSource
SKU: MBS3601762
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601762

A potent, selective, third-generation irreversible inhibitor of mutant EGFR with IC50s of 1/12/5 nM for L858R-T790M/L858R/L861Q respectively. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZD-9291, Biochemical

Full Product Name

AZD-9291

Product Synonym Names

Osimertinib; Mereletinib; AZD9291; AZD 9291

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

499.6073

Suitability

DMSO: >=30mg/mL

Target

EGFR

Receptor

EGFR (Exon19deletion); EGFR (L858R/T790M)

Chemical Name

2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]

SMILES

COC1=C(NC2=NC=CC(=N2)C2=CN(C)C3=CC=CC=C23)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C

Molecular Formula

C28H33N7O2

CAS Number

1421373-65-0

Product Categories/Family for AZD-9291 biochemical

Lung Cancer; Angiogenesis; Cancer

Product References and Citations for AZD-9291 biochemical

1. Finlay MR, et al. J Med Chem. 2014 Oct 23; 57 (20):8249-67.
2. Cross DA, et al. Cancer Discov. 2014 Sep; 4 (9):1046-61.
3. Eberlein CA, et al. Cancer Res. 2015 Jun 15; 75 (12):2489-500.

Other Notes

Small volumes of AZD-9291 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD-9291 purchase

MBS3601762 is a biochemical targeting AZD-9291.