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PF-05089771

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601822

PF-05089771 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 11 nM. More details

$285 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-05089771, Biochemical
Full Product Name
PF-05089771
Product Synonym Names
PF05089771
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
500.344
Target
Sodium Channel
Receptor
Na (V1.7) channel
Chemical Name
4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1, 3-thiazol-4-yl)benzenesulfonamide
SMILES
CC1=CC=C(C=C1)S(=O)(=O)O.C1=CC(=C(C=C1Cl)C2=C(NN=C2)N)OC3=CC(=C(C=C3Cl)S(=O)(=O)NC4=CSC=N4)F
Molecular Formula
C18H12Cl2FN5O3S2
CAS Number
1430806-04-4

Product Categories/Family for PF-05089771 biochemical

Pain; Membrane Transporter/Ion Channel; Neurological Disease

Structure of PF-05089771 biochemical

Pf-05089771 Biochemical – Cat# MBS3601822

Product References and Citations for PF-05089771 biochemical

1. Swain NA, et al. J Med Chem. 2017 Aug 24; 60 (16):7029-7042.
2. Theile JW, et al. Mol Pharmacol. 2016 Nov; 90 (5):540-548.
3. Alexandrou AJ, et al. PLoS One. 2016 Apr 6; 11 (4):e0152405.
4. Chernov-Rogan T, et al. Proc Natl Acad Sci U S A. 2018 Jan 23; 115 (4):E792-E801.

Other Notes

Small volumes of PF-05089771 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-05089771 purchase

MBS3601822 is a biochemical targeting PF-05089771.
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