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Firsocostat (ND-630)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601846

Firsocostat (ND-630, NDI-010976, GS-0976) is a highly potent, selective inhibitor of acetyl-CoA carboxylase (ACC) with IC50 of 2.1 and 6.1 nM for isozymes ACC1 and ACC2, respectively. More details

$290 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Firsocostat, Biochemical
Full Product Name
Firsocostat
Product Synonym Names
ND-630; NDI-010976; GS-0976
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
569.629
Suitability
DMSO: >=50mg/mL (87.78mM)
Target
ACC
Receptor
ACC
Chemical Name
2-[1-{(2R)-2-(2-methoxyphenyl)-2-[(oxan-4-yl)oxy]ethyl}-5-methyl-6-(1, 3-oxazol-2-yl)-2, 4-dioxo-1, 4-dihydrothieno[2, 3-d]pyrimidin-3(2H)-yl]-2-methylpropanoic acid
SMILES
O=C(O)C(C)(C)N(C(N(C[C@@H](C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC=CO5)S3)=O)C4=O
Molecular Formula
C28H31N3O8S
CAS Number
1434635-54-7

Product References and Citations for Firsocostat biochemical

1. Harriman G. et al. Proc Natl Acad Sci U S A. 2016 Mar 29; 113 (13):E1796-805.

Other Notes

Small volumes of Firsocostat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Firsocostat purchase

MBS3601846 is a biochemical targeting Firsocostat.
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