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Elacridar (GF-120918)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601856

A potent inhibitor of multidrug resistance (MDR) that fully reverses multidrug resistance CHRC5, OV1/DXR and MCF7/ADR cells to the cytotoxicity of doxorubicin and vincristine with IC50 of 0.02 uM. More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Elacridar, Biochemical
Full Product Name
Elacridar
Product Synonym Names
GF-120918; GW-0918; GG-918
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
563.6429
Suitability
10mM in DMSO
Target
P-glycoprotein
Receptor
P-gp (P-glycoprotein)
Chemical Name
4-Acridinecarboxamide, N-[4-[2-(3, 4-dihydro-6, 7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo
SMILES
COC1=CC=CC2=C1NC3=C(C2=O)C=CC=C3C(=O)NC4=CC=C(C=C4)CCN5CCC6=CC(=C(C=C6C5)OC)OC
Molecular Formula
C34H33N3O5
CAS Number
143664-11-3

Product References and Citations for Elacridar biochemical

1. Hyafil F, et al. Cancer Res. 1993 Oct 1; 53 (19):4595-602.
2. den Ouden D, et al. Leukemia. 1996 Dec; 10 (12):1930-6.
3. Witherspoon SM, et al. Clin Cancer Res. 1996 Jan; 2 (1):7-12.

Other Notes

Small volumes of Elacridar biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Elacridar purchase

MBS3601856 is a biochemical targeting Elacridar.
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