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GBT-440

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601895

A new potent allosteric effector of sickle cell hemoglobin; increases the affinity of hemoglobin for oxygen and consequently inhibits its polymerization when subjected to hypoxic conditions. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GBT-440, Biochemical
Full Product Name
GBT-440
Product Synonym Names
GBT 440; GBT440; Voxelotor
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
337.3725
Suitability
10mM in DMSO
Target
Other Targets
Receptor
Other Targets
Chemical Name
Benzaldehyde, 2-hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]
SMILES
O=CC1=C(OCC2=CC=CN=C2C3=CC=NN3C(C)C)C=CC=C1O
Molecular Formula
C19H19N3O3
CAS Number
1446321-46-5

Product Categories/Family for GBT-440 biochemical

Anemia; Other Indications

Structure of GBT-440 biochemical

GBT-440 Biochemical – Cat# MBS3601895

Product References and Citations for GBT-440 biochemical

1. Metcalf B, et al. ACS Med Chem Lett. 2017 Jan 23; 8 (3):321-326.
2. Oksenberg D, et al. Br J Haematol. 2016 Oct; 175 (1):141-53.
3. Dufu K, et al. Hematol Rep. 2016 Sep 28; 8 (3):6637.

Other Notes

Small volumes of GBT-440 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GBT-440 purchase

MBS3601895 is a biochemical targeting GBT-440.
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