Enasidenib (AG-221)

Name: Enasidenib (AG-221); MyBioSource
Brand: MyBioSource
SKU: MBS3601899
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601899

An orally available, selective, potent inhibitor of mutant IDH2 with IC50s of 100-400 nM for IDH2R140Q homodimer. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Enasidenib, Biochemical

Full Product Name

Enasidenib

Product Synonym Names

AG-221; CC-90007

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

473.375

Suitability

10mM in DMSO

Target

IDH

Receptor

IDH2

Chemical Name

2-Propanol, 2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1, 3, 5-triazin-2-yl]amino]

SMILES

CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O

Molecular Formula

C19H17F6N7O

CAS Number

1446502-11-9

Product Categories/Family for Enasidenib biochemical

Blood cancer; Metabolic Enzyme/Protease; Cancer

Product References and Citations for Enasidenib biochemical

1. Yen K, et al. Cancer Discov. 2017 May; 7 (5):478-493.
2. Kats LM, et al. Leukemia. 2017 Apr 11. doi: 10.1038/leu.2017.84.
3. Shih AH, et al. Cancer Discov. 2017 May; 7 (5):494-505.

Other Notes

Small volumes of Enasidenib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Enasidenib purchase

MBS3601899 is a biochemical targeting Enasidenib.