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CO-1686 hydrobromide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601900

A potent, highly selective, irreversible inhibitor of mutant EGFR with Ki of 21.5 nM for EGFR L858R/T790M. More details

$305 / 50 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CO-1686 hydrobromide, Biochemical
Full Product Name
CO-1686 hydrobromide
Product Synonym Names
Rociletinib hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
636.4634
Suitability
DMSO: >=59mg/mL
Target
EGFR
Receptor
EGFR
Chemical Name
2-Propenamide, N-[3-[[2-[[4-(4-acetyl-1-piperazinyl)-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-, hydrobromide(1:1)
SMILES
CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC.Br
Molecular Formula
C27H29BrF3N7O3
CAS Number
1446700-26-0

Product Categories/Family for CO-1686 hydrobromide biochemical

Breast Cancer; Angiogenesis; Cancer

Structure of CO-1686 hydrobromide biochemical

Co-1686 Hydrobromide Biochemical – Cat# MBS3601900

Product References and Citations for CO-1686 hydrobromide biochemical

1. Walter AO, et al. Cancer Discov. 2013 Dec; 3 (12):1404-15.
2. Tjin Tham Sjin R, et al. Mol Cancer Ther. 2014 Jun; 13 (6):1468-79.
3. Sequist LV, et al. N Engl J Med. 2015 Apr 30; 372 (18):1700-9.

Other Notes

Small volumes of CO-1686 hydrobromide biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CO-1686 hydrobromide purchase

MBS3601900 is a biochemical targeting CO-1686 hydrobromide.
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