Pralatrexate (NSC 754230)

Name: Pralatrexate (NSC 754230); MyBioSource
Brand: MyBioSource
SKU: MBS3601994
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601994

An antifolate that fuctions as a dihydrofolate reductase inhibitor for treatment of several malignancies. More details

$235 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pralatrexate, Biochemical

Full Product Name

Pralatrexate

Product Synonym Names

NSC 754230; PDX; 10-Propargyl-10-deazaaminopterin

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

477.4726

Suitability

10mM in DMSO

Target

Antifolate

Receptor

DHFR

Chemical Name

L-Glutamic acid, N-[4-[1-[(2, 4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]

SMILES

NC1=NC(N)=C2N=C(CC(CC#C)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=NC2=N1|r,c:15,17,32,35,t:1,4,6,13|

Molecular Formula

C23H23N7O5

CAS Number

146464-95-1

Product Categories/Family for Pralatrexate biochemical

Chemotherapeutic; Cell Cycle/DNA Damage; Cancer

Product References and Citations for Pralatrexate biochemical

1. DeGraw JI, et al. J Med Chem. 1993 Jul 23; 36 (15):2228-31.
2. Krug LM, et al. Clin Cancer Res. 2000 Sep; 6 (9):3493-8.
3. Wang ES, et al. Leuk Lymphoma. 2003 Jun; 44 (6):1027-35.
4. Molina JR. IDrugs. 2008 Jul; 11 (7):508-21.

Other Notes

Small volumes of Pralatrexate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pralatrexate purchase

MBS3601994 is a biochemical targeting Pralatrexate.