K-Ras G12C-in-12 (MDK-7958)

Name: K-Ras G12C-in-12 (MDK-7958); MyBioSource
Brand: MyBioSource
SKU: MBS3602005
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602005

An allosteric inhibitor of oncogenic K-Ras(G12C) with EC50 of 0.32 uM in H1792 cells. More details

$265 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

K-Ras G12C-IN-12, Biochemical

Full Product Name

K-Ras G12C-IN-12

Product Synonym Names

MDK-7958; MDK7958; MDK 7958; K-Ras (G12C) inhibitor 12

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

449.6713

Suitability

DMSO: >=48mg/mL

Target

Ras

Receptor

K-Ras (G12C)

Chemical Name

2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]

SMILES

C=CC(N1CCN(C(CNC2=CC(I)=C(Cl)C=C2O)=O)CC1)=O

Molecular Formula

C15H17ClIN3O3

CAS Number

1469337-95-8

Product Categories/Family for K-Ras G12C-IN-12 biochemical

MAPK/ERK Signaling; Cancer

Product References and Citations for K-Ras G12C-IN-12 biochemical

1. Ostrem JM, et al. Nature. 2013 Nov 28; 503 (7477):548-51.

Other Notes

Small volumes of K-Ras G12C-IN-12 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for K-Ras G12C-IN-12 purchase

MBS3602005 is a biochemical targeting K-Ras G12C-IN-12.