Fulacimstat (BAY 1142524)

Name: Fulacimstat (BAY 1142524); MyBioSource
Brand: MyBioSource
SKU: MBS3602057
Price: 365 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602057

Fulacimstat (BAY 1142524, BAY1142524) is a potent, orally available chymase inhibitor with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively. More details

$365 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fulacimstat, Biochemical

Full Product Name

Fulacimstat

Product Synonym Names

BAY 1142524; BAY1142524; BAY-1142524

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

487.39

Suitability

DMSO: 5mg/mL (10.26mM)

Target

Other Targets

Receptor

Other Targets

Chemical Name

1-(3-methyl-2-oxo-1, 3-benzoxazol-6-yl)-2, 4-dioxo-3-[(1R)-4-(trifluoromethyl)-2, 3-dihydro-1H-inden-1-yl]pyrimidine-5-carboxylic acid

SMILES

O=C(C1=CN(C2=CC=C3N(C)C(OC3=C2)=O)C(N([C@@H]4CCC5=C4C=CC=C5C(F)(F)F)C1=O)=O)O

Molecular Formula

C23H16F3N3O6

CAS Number

1488354-15-9

Product Categories/Family for Fulacimstat biochemical

Other Disease; Other Indications

Product References and Citations for Fulacimstat biochemical

1.Kanefendt F, et al. Clin Pharmacol Drug Dev. 2018 Jun 7. doi: 10.1002/cpdd.579.
2.Hanna Tinel, et al. Abstract 13624: A Novel Chymase Inhibitor BAY 1142524 Reduces Fibrosis and Improves Cardiac Function After Myocardial Infarction in Hamster. Circulation. 2017; 136:A13624.

Other Notes

Small volumes of Fulacimstat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fulacimstat purchase

MBS3602057 is a biochemical targeting Fulacimstat.