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CCT-245737 (SRA-737)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602060

A highly potent, selective, ATP-competitive inhibitor of Chk1 with IC50 of 1.3 nM; weak inhibition on Chk2 (IC50=2440 nM). More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCT-245737, Biochemical
Full Product Name
CCT-245737
Product Synonym Names
SRA-737; SRA737; SRA 737; CCT245737; CCT 245737
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
379.3398
Suitability
DMSO: >=32mg/mL
Target
Chk
Receptor
Chk1
Chemical Name
2-Pyrazinecarbonitrile, 5-[[4-[[(2R)-2-morpholinylmethyl]amino]-5-(trifluoromethyl)-2-pyridinyl]amino]
SMILES
N#CC1=NC=C(NC2=NC=C(C(F)(F)F)C(NC[C@H]3CNCCO3)=C2)N=C1
Molecular Formula
C16H16F3N7O
CAS Number
1489389-18-5

Product References and Citations for CCT-245737 biochemical

1. Osborne JD, et al. J Med Chem. 2016 Jun 9; 59 (11):5221-37.
2. Walton MI, et al. Oncotarget. 2016 Jan 19; 7 (3):2329-42.

Other Notes

Small volumes of CCT-245737 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCT-245737 purchase

MBS3602060 is a biochemical targeting CCT-245737.
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