Asciminib (ABL-001)

Name: Asciminib (ABL-001); MyBioSource
Brand: MyBioSource
SKU: MBS3602066
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602066

Asciminib (ABL-001) is a potent and selective allosteric ABL1 inhibitor with IC50 of 0.25 nM in BCR–ABL1-transformed BaF3 cells. More details

$260 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Asciminib, Biochemical

Full Product Name

Asciminib

Product Synonym Names

ABL-001

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

449.843

Suitability

DMSO: 50mg/mL
Water: Insoluble (<1mg/mL refers to the product slightly soluble or insoluble)

Target

Bcr-Abl

Receptor

Bcr-Abl

Chemical Name

(R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide

SMILES

C1CN(CC1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=CC=NN4

Molecular Formula

C20H18ClF2N5O3

CAS Number

1492952-76-7

Product Categories/Family for Asciminib biochemical

Blood cancer; Angiogenesis; Cancer

Product References and Citations for Asciminib biochemical

1. Wylie AA, et al. Nature. 2017 Mar 30; 543 (7647):733-737.
2. Lee BJ, et al. Leukemia. 2017 May; 31 (5):1096-1107.

Other Notes

Small volumes of Asciminib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Asciminib purchase

MBS3602066 is a biochemical targeting Asciminib.