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GNE-3511

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602076

GNE-3511 is a potent, selective, orally bioavailable, brain-penetrant dual leucine zipper kinase (DLK, MAP3K12) inhibitor with Ki of More details

$235 / 10 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNE-3511, Biochemical
Full Product Name
GNE-3511
Product Synonym Names
GNE3511; GNE 3511
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
440.489
Suitability
DMSO: >=32mg/mL
Target
MEK
Receptor
DLK; MAP3K12
Chemical Name
4-Pyridinecarbonitrile, 2-[[6-(3, 3-difluoro-1-pyrrolidinyl)-4-[1-(3-oxetanyl)-4-piperidinyl]-2-pyridinyl]amino]
SMILES
N#CC1=CC(NC2=NC(N3CC(F)(F)CC3)=CC(C4CCN(C5COC5)CC4)=C2)=NC=C1
Molecular Formula
C23H26F2N6O
CAS Number
1496581-76-0

Product Categories/Family for GNE-3511 biochemical

MAPK/ERK Signaling; Cancer

Structure of GNE-3511 biochemical

GNE-3511 Biochemical – Cat# MBS3602076

Product References and Citations for GNE-3511 biochemical

1. Patel S, et al. J Med Chem. 2015 Jan 8; 58 (1):401-18.

Other Notes

Small volumes of GNE-3511 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNE-3511 purchase

MBS3602076 is a biochemical targeting GNE-3511.
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