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Ro 46-2005

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602102

Ro 46-2005 is the first synthetic orally active nonpeptide antagonist of endothelin receptor with equipotent potency (IC50=0.2-0.5 uM) for ETA and ETB. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ro 46-2005, Biochemical
Full Product Name
Ro 46-2005
Product Synonym Names
Ro-462005
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
473.542
Suitability
DMSO: >=28mg/mL
Target
Endothelin Receptor
Receptor
ET-A; ET-B
Chemical Name
Benzenesulfonamide, 4-(1, 1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)-4-pyrimidinyl]
SMILES
O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=NC=NC(OCCO)=C2OC3=CC=CC(OC)=C3)=O
Molecular Formula
C23H27N3O6S
CAS Number
150725-87-4

Product Categories/Family for Ro 46-2005 biochemical

Hypertension; GPCR/G Protein; Cardiovascular Disease

Structure of Ro 46-2005 biochemical

Ro 46-2005 Biochemical – Cat# MBS3602102

Product References and Citations for Ro 46-2005 biochemical

1. Clozel M, et al. Nature. 1993 Oct 21; 365 (6448):759-61.
2. Breu V, et al. FEBS Lett. 1993 Nov 15; 334 (2):210-4.
3. Clozel M, et al. J Cardiovasc Pharmacol. 1993; 22 Suppl 8:S377-9.

Other Notes

Small volumes of Ro 46-2005 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ro 46-2005 purchase

MBS3602102 is a biochemical targeting Ro 46-2005.
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