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Epothilone B (EPO-906)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602121

A blood-brain barrier-permeable microtubule-stabilizing agent that promotes tubulin polymerization and induces G2-M cell cycle arrest with EC50 of 32 nM in HeLa cells. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Epothilone B, Biochemical
Full Product Name
Epothilone B
Product Synonym Names
EPO-906; Patupilone
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
507.6825
Suitability
10mM in DMSO
Target
Microtubule/Tubulin
Receptor
Tubulin
Chemical Name
4, 17-Dioxabicyclo[14.1.0]heptadecane-5, 9-dione, 7, 11-dihydroxy-8, 8, 10, 12, 16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-, (1S, 3S, 7S, 10R, 11S, 12S, 16R)
SMILES
C/C([C@@H](OC(C[C@H](O)C1(C)C)=O)C[C@H](O2)[C@@]2(C)CCC[C@H](C)[C@H](O)[C@@H](C)C1=O)=CC3=CSC(C)=N3
Molecular Formula
C27H41NO6S
CAS Number
152044-54-7

Product References and Citations for Epothilone B biochemical

1. Narvi E, et al. Br J Cancer. 2013 Jan 15; 108 (1):82-90.
2. Ruschel J, et al. Science. 2015 Apr 17; 348 (6232):347-52.
3. O'Reilly T, et al. Cancer Chemother Pharmacol. 2008 Nov; 62 (6):1045-54.

Other Notes

Small volumes of Epothilone B biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS3602121 is a biochemical targeting Epothilone B.
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