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SAR405

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602127

SAR405 is a highly potent and selective PI3K class III isoform Vps34 inhibitor with IC50 of 1.2 nM. More details

$250 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAR405, Biochemical
Full Product Name
SAR405
Product Synonym Names
SAR-405; SAR 405
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
443.8506
Suitability
DMSO: >=27mg/mL
Target
PI3K
Receptor
PI3K
Chemical Name
4H-Pyrimido[1, 2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6, 7, 8, 9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8S)
SMILES
O=C1C=C(N2[C@H](C)COCC2)N=C3N(CC4=CC(Cl)=CN=C4)[C@H](C(F)(F)F)CCN31
Molecular Formula
C19H21ClF3N5O2
CAS Number
1523406-39-4

Product Categories/Family for SAR405 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of SAR405 biochemical

SAR405 Biochemical – Cat# MBS3602127

Product References and Citations for SAR405 biochemical

1. Ronan B, et al. Nat Chem Biol. 2014 Dec; 10 (12):1013-9.
2. Pasquier B. Autophagy. 2015 Apr 3; 11 (4):725-6.
3. Valet C, et al. Blood. 2017 Nov 2; 130 (18):2032-2042.
4. New J, et al. Cancer Res. 2017 Dec 1; 77 (23):6679-6691.

Other Notes

Small volumes of SAR405 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAR405 purchase

MBS3602127 is a biochemical targeting SAR405.
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