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COH000

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602160

COH000 (COH-000) is a highly selective, first-in-class, irreversible, allosteric, covalent inhibitor of SUMO-Activating Enzyme E1. More details

$480 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COH000, Biochemical
Full Product Name
COH000
Product Synonym Names
COH-000; COH 000; CID 46835111; SID 99212997
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
419.477
Suitability
DMSO: Soluble (<1mg/mL refers to the product slightly soluble or insoluble)
Target
E1
Receptor
SUMO-activatingenzyme
Chemical Name
dimethyl 1-((R)-1-(phenylamino)-2-(p-tolyl)ethyl)-7-oxabicyclo[2.2.1]hepta-2, 5-diene-2, 3-dicarboxylate
SMILES
O=C(C1=C(C(OC)=O)C2C=CC1([C@H](NC3=CC=CC=C3)CC4=CC=C(C)C=C4)O2)OC
Molecular Formula
C25H25NO5
CAS Number
1534358-79-6

Product Categories/Family for COH000 biochemical

Proteasome/Ubiquitin

Structure of COH000 biochemical

COH000 Biochemical – Cat# MBS3602160

Product References and Citations for COH000 biochemical

1. Li YJ, et al. Cell Chem Biol. 2018 Dec 5. pii: S2451-9456 (18)30386-6. doi: 10.1016/j.chembiol.2018.10.026.

Other Notes

Small volumes of COH000 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COH000 purchase

MBS3602160 is a biochemical targeting COH000.
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