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CB-5083

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602188

CB-5083 is a potent, selective, orally bioavailable inhibitor of p97 AAA with IC50 of 11 nM. More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CB-5083, Biochemical
Full Product Name
CB-5083
Product Synonym Names
CB5083; CB 5083
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
413.4717
Suitability
10mM in DMSO
Target
p97
Receptor
p97
Chemical Name
1H-Indole-4-carboxamide, 1-[7, 8-dihydro-4-[(phenylmethyl)amino]-5H-pyrano[4, 3-d]pyrimidin-2-yl]-2-methyl
SMILES
O=C(C1=CC=CC2=C1C=C(C)N2C3=NC(NCC4=CC=CC=C4)=C(COCC5)C5=N3)N.
Molecular Formula
C24H23N5O2
CAS Number
1542705-92-9

Product Categories/Family for CB-5083 biochemical

Blood cancer; Proteasome/Ubiquitin; Cancer

Structure of CB-5083 biochemical

Cb-5083 Biochemical – Cat# MBS3602188

Product References and Citations for CB-5083 biochemical

1. Anderson DJ, et al. Cancer Cell. 2015 Nov 9; 28 (5):653-665.
2. Zhou HJ, et al. J Med Chem. 2015 Dec 24; 58 (24):9480-97.
3. Le Moigne R, et al. Mol Cancer Ther. 2017 Nov; 16 (11):2375-2386.
4. Bastola P, et al. Mol Oncol. 2016 Dec; 10 (10):1559-1574.

Other Notes

Small volumes of CB-5083 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CB-5083 purchase

MBS3602188 is a biochemical targeting CB-5083.
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