SGC0946

Name: SGC0946; MyBioSource
Brand: MyBioSource
SKU: MBS3602221
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602221

SGC0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM; selectively kill mixed lineage leukaemia cells. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SGC0946, Biochemical

Full Product Name

SGC0946

Product Synonym Names

SGC-0946; SGC 0946; SGC0946.

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

618.57

Suitability

Ethanol: 100mg/mL (161.66mM)
DMSO: 100mg/mL (161.66mM)

Target

HMTase

Receptor

DOT1L

Chemical Name

1-(3-((((2R, 3S, 4R, 5R)-5-(4-amino-5-bromo-7H-pyrrolo[2, 3-d]pyrimidin-7-yl)-3, 4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-isobutylphenyl)urea

SMILES

O=C(NC1=CC=C(CC(C)C)C=C1)NCCCN(C[C@H]2O[C@@H](N3C=C(Br)C4=C(N)N=CN=C43)[C@H](O)[C@@H]2O)C(C)C

Molecular Formula

C28H40BrN7O4

CAS Number

1561178-17-3

Product Categories/Family for SGC0946 biochemical

Chromatin/Epigenetic; Cancer

Product References and Citations for SGC0946 biochemical

1. Yu W, et al. nat Commun. 2012; 3:1288.

Other Notes

Small volumes of SGC0946 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS3602221 is a biochemical targeting SGC0946.

SGC0946

Product Overview

Product Categories/Family for SGC0946 biochemical

Structure of SGC0946 biochemical

Related Product Information for SGC0946 biochemical

Product References and Citations for SGC0946 biochemical

Other Notes

Searchable Terms for SGC0946 purchase